In the context of the speech production disorders observed in ENT cancers, neurological, sensory or structural pathologies, the objective of the RUGBI project is to make improvements to the measurement of the intelligibility deficit. Indeed, speech production disorders can lead to a serious loss of intelligibility, making it difficult for patients to communicate with those around them and limiting their professional and / or social life. Classically, the clinical evaluation of intelligibility is based on a global perceptual evaluation deemed unsatisfactory by its subjectivity, lack of precision and durationthat lead to erroneous measures of patient’s intelligibility. In addition, speech production tasksdedicated to this type of evaluation (repetition of words, sentences, reading) are far from being adapted to a precise measure of intelligibility and allow only an overall evaluation of the speech functional impairment. RUGBI proposes to overcome these limitations by developing a new objective evaluation tool based on i) the identification of relevant linguistic units from an acoustic and prosodic point of view, and ii) the identification of sensitive linguistic tasks. The objective of the RUGBI project is thus to supplement the therapist’s tools with a precise, robust and rapid measurement allowing to develop an optimized therapeutic project with a view to a tangible improvement of intelligibility. For this, RUGBI relies on important corpora, and already available speech productions of healthy subjects (190) and patients (365) presenting pathologies of structural origin (VADS cancers) and neurological (Parkinson’s disease), in the execution of different linguistic tasks, and for a part of them, at different stages of the disease. These corpora are a considerable asset for the conduct of the two areas of study of the project, respectively based on i) the perception of the speech intelligibility and ii) the automatic speech processing modeling, and more particularly, on the Deep Learning and its data representation properties that will have to be exploited here. In this context, the central objective of the project brings together the expertise of its members from the medical field, the field of language sciences and speech and language engineering to meet the challenges of biology and health. The multidisciplinary expertise thus acquired by RUGBI is a guarantee of success.